Relationship between Liver Stiffness Measured by Fibroscan and the Presence and Grading of Esophageal Varices by Endoscopy in Patients with Liver Cirrhosis

Background: Fibroscan (transient elastography) is a relatively new method of measuring liver stiffness and noninvasive fibrosis marker. The could be used as predictors oesophageal varices in cirrhotic patients because portal hypertension related to fibrosis. Objectives: This study aimed evaluate the diagnostic accuracy transient elastography for presence grade (EV) with cirrhosis. Methods: cross-sectional was conducted Department Medicine Gastroenterology Sylhet MAG Osmani Medical College Hospital, between July 2018 June 2019. Seventy two consecutive (mean age 47.21 ± 14.02 years, 73.6% males) were enrolled. Patients hepatocellular carcinoma, cirrhosis moderate or massive ascites, acute failure, previous variceal bleeding, treatment ß blockers, sclerotherapy band ligation varices, transjugular intrahepatic portosystemic shunt surgery hypertension, transplantation, portal, splenic hepatic vein thrombosis revealed by abdominal ultrasonography, Spontaneous bacterial peritonitis, extrahepatic cholestatsis, congestive cardia BMI 30 above excluded . All underwent fibroscan upper GI endoscopy. performance methods assessed using sensitivity, specificity, positive predictive value, negative receiver operating characteristic curves. Results: Oesophageal found 86.1% grade-I 22.2%, Grade-II 31.9%, Grade-III 31.9% no 13.9% patients. A significant correlation measured (r=0.568; p<0.001) (r=0.783; varices. best cutoff value measurement 14.45 kPa predicting sensitivity 98.4%, specificity 90.0%, (PPV) (NPV) 90% area under curve (AUROC) 0.967; 41.55 large (grade-II III) 95.7%, 92.3%, PPV NPV 92.3% AUROC 0.965. Conclusion: Liver correlated grading Measurement reliable larger endoscopy Therefore, it good test replace